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hmgbiotech HM-120
HMGB 1是細胞核的一個組成部分，在基因組的組織和表達中具有多種功能。HMG生物技術SRL為活躍在這一領域的其他研究人員和公司提供試劑、服務和想法。它還有助于實驗室開發(fā)分析和試劑。
hmgbiotech DISULFIDE HMGB1說明書
hmgbiotech HM-120
HMGB1是一種核蛋白，其由壞死細胞被動釋放，由凋亡細胞保留，并由炎癥細胞主動分泌（Dumitriu等人，HMGB1:從內(nèi)部引導免疫。Trends Immunol 2005，26:381-7）。HMGB1對生命至關重要：HMGB1基因敲除小鼠出生后不久死亡。
HMGB1作為運動細胞的化學引誘劑和細胞因子的誘導劑的兩種不同活性被歸因于不同的生物化學形式。還原的HMGB1（具有化學引誘活性的形式）被還原；二硫化物HMGB1包含C23和C45之間的二硫鍵（完整注釋：HMGB1C23-C45C106h–Antoine J.等人（2014）。Mol-Med）。
二硫化物HMGB1可誘導單核細胞和其他炎癥細胞產(chǎn)生細胞因子和趨化因子（Venereau等人，2012）。
在結構上，二硫化物HMGB1在半胱氨酸殘基23和45與還原的半胱氨酸殘基106之間具有二硫鍵。測試二硫化物HMGB1刺激細胞因子的能力
HMGBiotech公司熱銷產(chǎn)品
產(chǎn)品名稱 | 貨號 |
100 ug Fully reduced HMGB1, LPS free | HM-115 |
50 ug Fully reduced HMGB1, LPS free | HM-116 |
100 ug Disulfide HMGB1, LPS free | HM-121 |
100 ug BoxA from HMGB1, LPS-free and tested in migration assay | HM-012 |
50 ug Disulfide HMGB1, LPS free | HM-122 |
500 ug BoxA from HMGB1, LPS-free and tested in migration assay | HM-013 |
1 mg HMGB1 for biochemistry | HM-100 |
2.5 mg BoxA from HMGB1, LPS-free and tested in migration assay | HM-014 |
250 ug HMGB1 biochemistry | HM-101 |
25 ug BoxA from HMGB1, LPS-free and tested in migration assay | HM-011 |
15 ug BoxB from HMGB1, LPS-free and tested in migration assay | HM-053 |
15 ug Fully reduced HMGB1, LPS free | HM-117 |
10 ug Disulfide HMGB1, LPS free | HM-123 |
15 ug Non-oxidizable HMGB1, LPS free | HM-133 |
250 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | HM-170 |
100 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | HM-171 |
50 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | HM-172 |
15 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | HM-173 |
50 ug HMGB1 15N labelled for Mass Spectrometry | HM-180 |
5 ug HMGB1 15N labelled for Mass Spectrometry | HM-181 |
2.5 mg BoxA 2D from HMGB1, LPS-free and tested in migration assay | HM-190 |
500 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay | HM-191 |
100 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay | HM-192 |
25 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay | HM-193 |
Control cell lysates from Hmgb1 +/+ | HM-001 |
Control cell lysates from Hmgb1 -/- | HM-002 |
1 mg BoxB from HMGB1, LPS-free and tested in migration assay | HM-050 |
250 ug BoxB from HMGB1, LPS-free and tested in migration assay | HM-051 |
100 ug BoxB from HMGB1, LPS-free and tested in migration assay | HM-052 |
500 ug Fully reduced HMGB1, LPS free | HM-114 |
250 ug Disulfide HMGB1, LPS free | HM-120 |
500 ug Non-oxidizable HMGB1, LPS free | HM-130 |
100 ug Non-oxidizable HMGB1, LPS free | HM-131 |
50 ug Non-oxidizable HMGB1, LPS free | HM-132 |
500 ug HMGB2, LPS-free and tested in migration assay | HM-151 |
100 ug HMGB2, LPS-free and tested in migration assay | HM-152 |
50 ug HMGB2, LPS-free and tested in migration assay | HM-153 |
Embryonic fibroblasts immortalized with large T antigen. One vial of -/- cells and one vial of +/+ cells | HM-201 |
Embryonic fibroblasts immortalized with the 3T3 method. One vial of -/- cells and one vial of +/+ cells | HM-221 |
Embryonic fibroblasts, Hmgb1-/- and HMGB2-low, immortalized with the 3T3 method. One vial of cells, and | HM-223 |
HMGB1 Isoforms Kit - Test size | HM-030 |
Embryonic fibroblasts immortalized with the 3T3 method. One vial of Hmgb2-/- cells and one vial of +/+ cells | HM-251 |
HMGB1 Isoforms Kit - Regular size | HM-031 |
20 ug p-mHMG1 | HM-300 |
50 ug Terminally oxidized HMGB1, LPS free | HM-062 |
20 ug p-mHMG1tag | HM-301 |
100 ug Terminally oxidized HMGB1, LPS free | HM-061 |
20 ug pEGFP-HMGB1 | HM-302 |
250 ug Terminally oxidized HMGB1, LPS free | HM-060 |
20 ug pcDNA/FL-RAGE plasmid | HM-310 |
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